The Drug Enforcement Administration on Wednesday disclosed that it intercepted 379m potentially deadly fentanyl doses.
According to the Mirror, the US federal drug agent stated that the seized drugs are enough to kill every American.
The most deadly drug threat to the US, according to the DEA, is the extremely addictive narcotic that is 50 times as potent as heroin.
According to the DEA, Mexico is the main source of fentanyl trafficking into the US.
More than 10,000lb (4,500kg) of fentanyl and more than 50.6 million fentanyl tablets that were designed to seem like various prescription medications were reportedly recovered, according to the DEA.
According to the government, the majority of the drugs were mass-produced at secret Mexican factories by the Sinaloa and Jalisco drug cartels, who use chemicals sourced from China.
A deadly dose of the medication is small enough to fit on the tip of a pencil.
Last year, over 100,000 Americans died from opioid overdoses, with fentanyl accounting for two-thirds of those deaths. According to the drug administration, the amount of fentanyl collected this year was enough to kill all 330 million Americans.